Presentations
November 18th, 2024
ESPE 2024- Liverpool,UK – Late Breaking Oral Presentation
Oral Presentation:
"The Amount and Pattern Of Pulsatile GH Secretion Induced By The Oral Growth Hormone Secretagogue LUM-201 Is Related To Growth And IGF-1 Responses In Moderate Pediatric Growth Hormone Deficiency (PGHD)”
Peter Clayton, MD, Univ. of Manchester, UK
November 17th, 2024
ESPE 2024- Liverpool,UK – Oral Presentation
Oral Presentation:
“Growth, IGF-1 and IGFBP-3 Responses to Oral LUM-201 in OraGrowtH210 and OraGrowtH212 Trials in Pediatric Growth Hormone Deficiency (PGHD) over 12 to 24 Months on Treatment”
Elżbieta Petriczko, MD, Pomeranian Medical University in Szczecin, Poland
October 3rd, 2024
APPES 2024- New Delhi, India – Oral Presentation
Oral Presentation:
“Growth, IGF-1 and IGFBP-3 Responses to the Oral Growth Hormone (GH) Secretagogue, LUM-201, in Pediatric Growth Hormone Deficiency (PGHD) in the OraGrowtH210 Trial”
Paul Hofman, MD, University of Auckland, New Zealand
September 13th, 2024
SLEP 2024 – Santiago, Chile, E-Poster Presentation
E-Poster Presentation:
“LUM-201 Restores Growth Hormone Secretion and Promotes Growth in Moderate Pediatric Growth Hormone Deficiency (PGHD): Phase 2 Topline Results from OraGrowtH210 and OraGrowtH212 Trials”
Rossana Román, MD, Institute of Maternal and Child Research, University of Chile, Santiago, Chile
June 3rd, 2024
ENDO 2024 – Boston, MA, USA – Late Breaking Poster
Late Breaking Session: Poster Presentation (MON-704):
“Growth Response to Oral Growth Hormone Secretagogue LUM-201 in Children with Moderate GH Deficiency (GHD) is Dependent on the Pattern of Pulsatile GH Secretion Stimulated by LUM-201”
Adam Stevens, PhD, University of Manchester, Manchester, UK
June 3rd, 2024
ENDO 2024 – Boston, MA, USA – Poster Presentations
Poster Presentation (MON-111):
“Oral LUM-201 Restores Pulsatile Growth Hormone Secretion and Growth Response in Moderate Pediatric Growth Hormone Deficiency (PGHD): Key Discoveries from Phase 2 of OraGrowtH212 Trial”
Fernando Cassorla, MD, University of Chile, Santiago, Chile
May 21st, 2024
European Congress of Endocrinology (ECE) 2024- Stockholm,Sweden – Poster Presentation
Poster Presentation:
“Approaching the Reality of Restoring GH Secretion and Growth with LUM-201, the Investigative Oral Growth Hormone Secretagogue (GHS) in moderate Pediatric Growth Hormone Deficiency (PGHD)”
Peter Clayton, MD, University of Manchester, Manchester, UK
May 10th, 2024
Growth Research Society(GRS) 2024- Stockholm, Sweden – Oral Presentation
Oral Presentation:
“Approaching the Reality of Restoring GH Secretion and Growth with LUM-201, the Investigative Oral Growth Hormone Secretagogue (GHS) in moderate Pediatric Growth Hormone Deficiency (PGHD)”
Peter Clayton, MD, University of Manchester, Manchester, UK
May 3rd, 2024
Pediatric Endocrine Society PES 2024 – Chicago, Illinois, USA – Poster Presentation
Poster Presentation:
“OraGrowtH210 Trial (Phase 2): Oral LUM-201 Shows Similar Annualized Height Velocity to Daily rhGH in Moderate Pediatric Growth Hormone Deficiency (PGHD) with a 1.6mg/kg/day Dose and a Promising Investigational Safety Record”
Andrew Dauber, MD,Children’s National Medical Center, Washington DC, USA
September 23rd, 2023
European Society of Pediatric Endocrinology (ESPE) 2023- The Hague, Netherlands – Late Breaking Oral Presentation
Late Breaking Oral Presentation:
“Deconvolution Analysis: Oral GH secretagogue (LUM-201) enhances growth in individuals with moderate Pediatric Growth Hormone Deficiency (PGHD) by enhancing endogenous GH secretion and increasing IGF-1”
Fernando Cassorla, MD, University of Chile, Santiago, Chile
June 17th, 2023
ENDO 2023 - Chicago, Illinois, USA – Second Oral Presentations
Oral Presentation:
“Dose Responsiveness of LUM-201 as Measured by Acute GH Response and IGF-1 and Annualized Height Velocity (AHV) Measured at 6 Months in the Interim Analysis of the OraGrowtH212 Study in Idiopathic Pediatric Growth Hormone Deficiency (iPGHD)”
Fernando Cassorla, MD, University of Chile, Santiago, Chile
June 17th, 2023
ENDO 2023 - Chicago, Illinois, USA – First Oral Presentations
Oral Presentation:
“Response of Oral LUM-201 in OraGrowtH210 and OraGrowtH212 Trials in Idiopathic Pediatric Growth Hormone Deficiency (iPGHD): Combined Analysis Interim Analysis Data”
Michael Tansey, MD, University of Iowa, Iowa City, Iowa USA
May 7th, 2023
PES 2023 - San Diego, California, USA – Oral Presentation
Oral Presentation:
“Growth Response to LUM-201 in the OraGrowtH210 Trial in Idiopathic Pediatric Growth Hormone Deficiency (iPGHD): Interim Analysis Data (41 subjects)”
Andrew Dauber, MD, Childrens National Medical Center, Washington DC, USA
May 6th, 2023
PES 2023 - San Diego, California, USA – Poster
Poster:
“Observed Serum IGF-1 Concentration Increase Within Normal Range After Prolonged Daily Oral LUM-201 Administration in Idiopathic Pediatric Growth Hormone Deficiency from the OraGrowtH212 Trial: Interim Analysis Data“
March 5th-7th, 2023
IMPE 2023 - Buenos Aires, Argentina – Poster
Poster:
“LUM-201 in Idiopathic Pediatric Growth Hormone Deficiency (iPGHD) Interim Analysis on Baseline Demographics, Safety Profile and 6 month Annualized Height Velocity (AHV) from the OraGrowtH210 Trial”
Alison Lunsford, MD, Texas Tech HSC, Amarillo, Texas, USA
March 5th, 2023
IMPE 2023 - Buenos Aires, Argentina – Oral Presentation
Oral Presentation:
“Dose-dependent Increase in GH AUC0-12h with LUM- 201 in Idiopathic Pediatric GH Deficiency from the Interim Analysis Data of the OraGrowtH212 Trial”
Fernando Cassorla, MD, University of Chile, Santiago, Chile
March 20th-23rd, 2021
ENDO 2021 - Virtually Held Meeting – Poster
Poster:
“LUM-201 Elicits Greater GH Response than Standard GH Secretagogues in Pediatric Growth Hormone Deficiency”
George Bright, MD, Lumos Pharma, Austin, TX, USA
Publications
March 30th, 2022
A GH Secretagogue Receptor Agonist (LUM-201) Elicits Greater GH Responses than Standard GH Secretagogues in Subjects of a Pediatric GH Deficiency Trial
George M Bright, MD; Michael O Thorner, MB, BS, DSc
February 25th, 2021
Development of a Predictive Enrichment Marker for Oral GH Secretagogue LUM-201 in Children with Growth Hormone Deficiency
George M Bright, MD; Minh-Ha T Do, PhD; John C McKew, PhD; Werner F Blum, MD; Michael O Thorner, MB, BS, DSc
February 25th, 2021
Corroboration of Height Velocity Prediction Markers for rhGH with an Oral GH Secretagogue Treatment in Children with GHD
Werner F Blum, MD; George M Bright, MD; Minh-Ha T Do, PhD; John C McKew, PhD; Haiying Chen, MD, PhD; Michael O Thorner, MB, BS, DSc
